The first Second City Anthropology Conference was held on March 3, 2012. The conference was organized by the students of the UIC Graduate Anthropology and Geography Association, with assistance from the UIC Department of Anthropology. Additional financial support was provided by The Field Museum and several institutions at UIC, including the Student Activities Funding Committee, Institute for Humanities, Catering, Great Cities Institute, LAS Dean's Office, and the Graduate Student Council.

The late Dr. Neil Smith gave the keynote address, entitled "2011 and All That: From Ideology to the Confluence of Revolts." To watch a video of the talk, please follow this link: https://www.youtube.com/watch?v=KgQACtEhAMs.